Drug Discovery Lead - Cell Therapy
Company: Takeda Pharmaceutical
Location: Boston
Posted on: October 30, 2024
Job Description:
By clicking the "Apply" button, I understand that my employment
application process with Takeda will commence and that the
information I provide in my application will be processed in line
with Takeda's and . I further attest that all information I submit
in my employment application is true to the best of my
knowledge.Job DescriptionAre you looking for a patient-focused,
innovation-driven company that will inspire you and empower you to
shine? Join us as a (Title) in our Cambridge office.At Takeda, we
are transforming the pharmaceutical industry through our
R&D-driven market leadership and being a values-led company. To
do this, we empower our people to realize their potential through
life-changing work. Certified as a Global Top Employer, we offer
stimulating careers, encourage innovation, and strive for
excellence in everything we do. We foster an inclusive,
collaborative workplace, in which our global teams are united by an
unwavering commitment to deliver Better Health and a Brighter
Future to people around the world.Here, you will be a vital
contributor to our inspiring, bold mission.Takeda is proud in its
commitment to creating a diverse workforce and providing equal
employment opportunities to all employees and applicants for
employment without regard to race, color, religion, sex, sexual
orientation, gender identity, gender expression, parental status,
national origin, age, disability, citizenship status, genetic
information or characteristics, marital status, status as a Vietnam
era veteran, special disabled veteran, or other protected veteran
in accordance with applicable federal, state and local laws, and
any other characteristic protected by lawObjective / Purpose: The
Drug Discovery Lead (DDL) serves as a strategic leader within the
Oncology Drug Discovery Unit (ODDU) and is a member of the ODDU
Leadership Team reporting into the Global Head of the ODDU. - This
pivotal role entails overseeing the entire drug discovery
continuum, from target identification, concept validation, asset
generation, and clinical positioning in collaboration with internal
and external research partners and in alignment with the Oncology
Therapeutic Area Unit including translation strategy. - The DDL's
global strategic leadership, scientific expertise, and business
acumen are essential for advancing Takeda's Oncology pipeline
through early clinical proof of concept for both internal and
external assets with a particular emphasis on assets leveraging
innate cell therapies.Accountabilities: - - - - - - - - - - - - - -
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- Drive the strategic evolution, direction and leadership for an
established Solid and Heme Tumor Cell Therapies team in the
Oncology Drug Discovery Unit, ensuring alignment with the company's
goals and objectives that deliver game-changing, highly
differentiated, therapeutic opportunities for patients.
- Lead and manage multiple drug discovery projects, overseeing
the entire drug development process from target identification to
preclinical development.---
- Collaborate and enable teams to collaborate with
cross-functional teams, including Global Biologics, Cell Therapy
Technology and Product Engine, along with other research partners
within and external to Takeda. to develop and execute drug
discovery strategies.---
- Drive the identification and validation of novel approaches to
maximize cell therapy platforms through the application of
cutting-edge technologies and scientific approaches aligned with
the iDAS (integrated disease area strategy).---
- Foster a culture of innovation and scientific excellence within
the drug discovery team, promoting collaboration, knowledge
sharing, and continuous learning.---
- Evaluate and prioritize potential drug candidates based on
scientific, medical, and commercial considerations.---
- Oversee the design and execution of experiments, data analysis,
and interpretation to guide decision-making and optimize drug
discovery efforts.---
- Stay abreast of the latest advancements in drug discovery,
emerging technologies, and industry trends, and apply this
knowledge to enhance drug discovery strategies.---
- Build and maintain relationships with key stakeholders,
including academic institutions, research organizations, and
industry partners.---
- Provide guidance and mentorship to team members, fostering
their professional growth and development.
- Represents Takeda externally and plays a key role in evaluating
external opportunities (e.g. serve on critical pipeline-enabling
partnerships
- Be an effective ambassador for the Takeda global business
development brand to ensure Takeda is perceived as a "Partner of
Choice" with outside organizations, companies, etc.
- Create BD opportunities that meet the strategic scientific,
therapeutic and commercial needs of the organization or specific
Therapeutic Area (TA). -
- Working with the CEI Therapeutic Area Leads and other key
functions outside of business development, help design and
implement processes for opportunity assessment and due diligence to
ensure competitive superiority.
- Establish and maintain a broad network of relationships
internally and external to Takeda; liaise effectively with other
individuals in global business development and leverage the Takeda
organization at large (scientists, clinicians, commercial managers
in oncology and other therapeutic areas) to ensure maximal sourcing
capability for the assigned area.
- Effectively motivates and retains top talent and, where needed,
builds new expert teams
- Is recognized as an international subject matter expert and
identified as a global Takeda thought leaderEducation &
Competencies: -
- Advanced degree in health or life sciences (e.g., Ph.D., M.D.,
D.V.M.) with 15 years industry and 15 years management
experience.
- Extensive experience in leading drug discovery teams and
managing drug development projects, preferably in a pharmaceutical
or biotechnology setting.
- Extensive experience leading multiple assets from preclinical
into development
- Proven track record of successful drug discovery programs,
including the identification and optimization of lead
compounds.
- Deep understanding of the drug discovery process, including
target identification, hit-to-lead optimization, and preclinical
development.
- Strong subject matter expertise in immune-oncology, cell
therapy drug discovery and development including CMC
considerations, CAR design, engineering and armoring strategies,
innate immune cells such as NK and gamma delta for the purposes of
leading drug development projects from start to the clinic.
- Strong knowledge of various drug discovery techniques, such as
high-throughput screening, molecular modeling, and
structure-activity relationship analysis, and CMC awareness.
- Excellent leadership and strategic planning skills, with the
ability to inspire and motivate teams towards achieving ambitious
goals.
- Strong business acumen and understanding of the pharmaceutical
industry, including regulatory requirements and commercial
considerations.
- Exceptional communication and presentation skills, with the
ability to effectively communicate complex scientific concepts to
diverse audiences.
- Proven ability to build and maintain collaborative
relationships with internal and external stakeholders.
- Strong problem-solving and decision-making abilities, with a
focus on data-driven approaches.
- Extensive knowledge of drug development regulations and
processes, including IND and NDA submissions
- Demonstrated success in building and managing high impact
strategic partnerships with academic institutions, research
organizations, and industry collaborators.
- Experience in leading drug discovery programs targeting
specific therapeutic areas.
- Knowledge of drug development regulations and processes,
including IND and NDA submissions.
- Demonstrated success in building and managing strategic
partnerships with academic institutions, research organizations,
and industry collaborators.
- Takeda's high-engagement and ONE Research DEI culture is an
important factor in our success; we seek team members who will
contribute to and further strengthen that culture in all ways of
working.#LI-JT1Takeda Compensation and Benefits SummaryWe
understand compensation is an important factor as you consider the
next step in your career. We are committed to equitable pay for all
employees, and we strive to be more transparent with our pay
practices. -For Location:Boston, MAU.S. Base Salary
Range:$205,100.00 - $322,300.00The estimated salary range reflects
an anticipated range for this position. The actual base salary
offered may depend on a variety of factors, including the
qualifications of the individual applicant for the position, years
of relevant experience, specific and unique skills, level of
education attained, certifications or other professional licenses
held, and the location in which the applicant lives and/or from
which they will be performing the job.---The actual base salary
offered will be in accordance with state or local minimum wage
requirements for the job location. -U.S. based employees may be
eligible for short-term and/ or long-term incentives. U.S. based
employees may be eligible to participate in medical, dental, vision
insurance, a 401(k) plan and company match, short-term and
long-term disability coverage, basic life insurance, a tuition
reimbursement program, paid volunteer time off, company holidays,
and well-being benefits, among others. U.S. based employees are
also eligible to receive, per calendar year, up to 80 hours of sick
time, and new hires are eligible to accrue up to 120 hours of paid
vacation. -EEO StatementTakeda is proud in its commitment to
creating a diverse workforce and providing equal employment
opportunities to all employees and applicants for employment
without regard to race, color, religion, sex, sexual orientation,
gender identity, gender expression, parental status, national
origin, age, disability, citizenship status, genetic information or
characteristics, marital status, status as a Vietnam era veteran,
special disabled veteran, or other protected veteran in accordance
with applicable federal, state and local laws, and any other
characteristic protected by law.LocationsBoston, MAWorker
TypeEmployeeWorker Sub-TypeRegularTime TypeFull time
Keywords: Takeda Pharmaceutical, Brookline , Drug Discovery Lead - Cell Therapy, Other , Boston, Massachusetts
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