Sr. Scientist, Protein Biochemistry

Company: HireMinds
Location: Boston
Posted on: November 20, 2024

Job Description:

Sr. Scientist, Protein BiochemistryLocation: Boston, MassachusettsHireMinds is representing a clinical-stage biopharmaceutical client that is leading the way in developing biologics. Our client's approach allows them to selectively engage and modulate disease-specific T cells, aiming to transform the treatment landscape for cancer, autoimmune, and inflammatory diseases. Located in an exciting new lab space in Boston's vibrant life sciences corridor, they have a collaborative team with hands-on leadership that is present and invested in the team's success.You'll Be Responsible For:

• Working as a Scientist or Senior Scientist in a Protein Discovery team with hands-on skills in protein purification and protein characterization.
• Working on mammalian expression of products including engineered Fc-fusion and recombinant proteins.
• Performing protein purification with affinity, ion-exchange (IEX), and size-exclusion chromatography (SEC).
• Progressing programs into downstream testing in Quality Control and characterization utilizing methods including SE-HPLC, SDS-PAGE, UV-Vis spectroscopy, and ELISA.
• Designing and executing buffer screens and assays to optimize formulations of protein therapeutics.
• Bringing experience with optimization of protein conjugation and purification processes.
• Presenting findings through well-structured documentation and engaging oral presentations to peers and management teams.
• Managing routine maintenance of instrumentation vital to protein biochemistry and collaborating with vendors when necessary.You'll Bring With You:
• B.S. or M.S. in pharmaceutical, biological, or chemical sciences with 7-8 years of industry experience, or a Ph.D. in a relevant field with 2 years of industrial experience in Biotech or Biopharma.
• Strong hands-on experience in protein purification and a solid grasp of protein biochemistry.
• Hands-on experience with instrumentation, including AKTA systems and bioanalytical techniques: HPLC, DSC, SEC-MALS, DSF.
• Proven ability to design and carry out biochemical or biological assays.
• Previous experience with protein conjugation chemistry is preferred.This position offers an extraordinary chance for protein biochemists eager to make a significant impact on drug discovery while expanding their professional skills in a collaborative and innovative setting. Become part of our client's mission to redefine treatment options for patients.
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Keywords: HireMinds, Brookline , Sr. Scientist, Protein Biochemistry, Other , Boston, Massachusetts